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Diabetic Nephropathy

Go to Protective Genes for Nephropathy

Locus_Id Gene_Symbol Chromosome Homologene_Id Gene_Name Synonyms
1636ACE1737351angiotensin I converting enzymeDCP, ICH, ACE1, DCP1, CD143, MVCD3
59272ACE2X41448angiotensin I converting enzyme 2ACEH
94ACVRL11220058activin A receptor type II-like 1HHT, ALK1, HHT2, ORW2, SKR3, ALK-1, TSR-I,
102ADAM1015865ADAM metallopeptidase domain 10RAK, kuz, AD10, AD18, MADM, CD156c, HsT18717
6868ADAM1722395ADAM metallopeptidase domain 17CSVP, TACE, NISBD, ADAM18, CD156B, NISBD1
11093ADAMTS13916372ADAM metallopeptidase with thrombospondin type 1 motif, 13VWFCP, C9orf8, vWF-CP, ADAM-TS13, ADAMTS-13
116ADCYAP118869adenylate cyclase activating polypeptide 1 (pituitary)PACAP
125ADH1B4133563alcohol dehydrogenase 1B (class I), beta polypeptideADH2, HEL-S-117
9370ADIPOQ33525adiponectin, C1Q and collagen domain containingACDC, ADPN, APM1, APM-1, GBP28, ACRP30, ADIPQTL1
133ADM11873adrenomedullinAM, PAMP
173AFM4881 afaminALF, ALB2, ALBA
177AGER6883advanced glycosylation end product-specific receptorRAGE
183AGT114angiotensinogen (serpin peptidase inhibitor, clade A, member 8)ANHU, SERPINA8
185AGTR133556angiotensin II receptor, type 1AT1, AG2S, AT1B, AT1R, AT1AR, AT1BR, AT2R1,
10598AHSA1148106AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)p38, AHA1, hAha1, C14orf3
197AHSG31225alpha-2-HS-glycoproteinAHS, A2HS, HSGA, FETUA
231AKR1B17133743aldo-keto reductase family 1, member B1 (aldose reductase)AR, ADR, ALR2, ALDR1
57016AKR1B107116462aldo-keto reductase family 1, member B10 (aldose reductase)HIS, HSI, ARL1, ARL-1, ALDRLn, AKR1B11, AKR1
207AKT1143785v-akt murine thymoma viral oncogene homolog 1AKT, PKB, RAC, CWS6, PRKBA, PKB-ALPHA, RAC-A
213ALB4405albuminFDAH, ANALBA, PRO0883, PRO0903, PRO1341
214ALCAM31229activated leukocyte cell adhesion moleculeMEMD CD166
216ALDH1A19110441aldehyde dehydrogenase 1 family, member A1ALDC, ALDH1, HEL-9, HEL12, PUMB1, ALDH11, RALDH1,
217ALDH21255480aldehyde dehydrogese 2 family (mitochondrial)ALDM, ALDHI, ALDH-E2
239ALOX1217560arachidonate 12-lipoxygenase, 12S typeLOG12, 12-LOX, 12S-LOX
241ALOX5AP131231arachidonate 5-lipoxygenase-activating proteinFLAP
80216ALPK1411849alpha kinase 1LAK, 8430410J10Rik
249ALPL137314alkaline phosphatase, liver/bone/kidneyHOPS, TP, APTP, TNSALP, AP-TP
259AMBP91234alpha-1-microglobulin/bikunin precursorA1M, HCP, ITI, UTI, EDC1, HI30, ITIL, IATIL, ITILC
283ANG1474385angiogenin, ribonuclease, RNase A family, 5ALS9, RAA1, HEL168, RNASE4, RNASE5
23452ANGPTL2922695angiopoietin-like 2ARP2, HARP
51129ANGPTL41910755angiopoietin-like 4NL2, ARP4, FIAF, HARP, PGAR, HFARP, TGQTL, UNQ171,
314AOC21756457amine oxidase, copper containing 2 (retina-specific)RAO, DAO2
324APC530950adenomatous polyposis coliGS, DP2, DP3, BTPS2, DP2.5, PPP1R46
187APLNR113784apelin receptorAPJ, APJR, HG11, AGTRL1
341APOC119136749apolipoprotein C-IApo-CI, ApoC-I
345APOC31181615apolipoprotein C-IIIHALP2, APOCIII
348APOE1930951apolipoprotein EAD2, LPG, LDLCQ5
8542APOL122apolipoprotein L1APOL, APO-L, FSGS4, APOL-I
26060APPL1332143adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1APPL, DIP13alpha
359AQP21220137aquaporin 2AQP-CD WCH-CD
362AQP51220398aquaporin 5PPKB, AQP-5
367ARX28androgen receptorKD, AIS, AR8, TFM, DHTR, SBMA, HYSP1, NR3C4, SMAX1
468ATF4221266activating transcription factor 4CREB2, TXREB, CREB-2, TAXREB67
567B2M152987beta-2-microglobulinNONE
25805BAMBI108215BMP and activin membrane-bound inhibitorNMA
10409BASP1538168brain abundant, membrane attached signal protein 1CAP23, NAP22, CAP-23, NAP-22
596BCL218527B-cell CLL/lymphoma 2Bcl-2, PPP1R50
652BMP4147247bone morphogenetic protein 4ZYME,BMP2B,OFC11,BMP2B1,MCOPS6
718C31968031 complement C3 ASP C3a C3b AHUS5 ARMD9 CPAMD1 HEL-S-62p
727C5920412complement component 5C5D, C5a, C5b, ECLZB, CPAMD4
10498CARM11910990coactivator-associated arginine methyltransferase 1PRMT4
847CAT1155514catalaseNONE
857CAV171330caveolin 1, caveolae protein, 22kDaCGL3, PPH3, BSCL3, LCCNS, VIP21, MSTP085
885CCK3583cholecystokinin
886CCKAR437337cholecystokinin A receptorCCK-A, CCKRA, CCK1-R
6347CCL2172245chemokine (C-C motif) ligand 2HC11, MCAF, MCP1, MCP-1, SCYA2, GDCF-2, SMC-CF, HS
6364CCL2023375chemokine (C-C motif) ligand 20CKb4, LARC, ST38, MIP3A, MIP-3a, SCYA20, MIP
6352CCL5172244C-C motif chemokine ligand 5SISd, eoCP, SCYA5, RANTES, TCP228, D17S136E, SIS-d
1230CCR1320344chemokine (C-C motif) receptor 1CKR1, CD191, CKR-1, HM145, CMKBR1, MIP1aR, SCYAR1
729230CCR23537chemokine (C-C motif) receptor 2CKR2, CCR-2, CCR2A, CCR2B, CD192, CKR2A, CKR2B, CM
1234CCR5337325chemokine (C-C motif) receptor 5 (gene/pseudogene)CKR5, CCR-5, CD195, CKR-5, CCCKR5, CMKBR5, IDDM22,
23607CD2AP67663CD2-associated proteinCMS
948CD36773871CD36 molecule (thrombospondin receptor)FAT, GP4, GP3B, GPIV, CHDS7, PASIV, SCARB3, BDPLT1
952CD3841345CD38 moleculeT10
959CD40LGX56CD40 ligandIGM,IMD3,TRAP,gp39,CD154, CD40L, HIGM1,T-BAM, T
961CD4731346CD47 moleculeIAP, OA3, MER6
967CD631237526CD63 moleculeMLA1, ME491, LAMP-3, OMA81H, TSPAN30
968CD6817955CD68 moleculeGP110, LAMP4, SCARD1
969CD6912128584CD69 moleculeAIM, EA1, MLR-3, CLEC2C, GP32/28, BL-AC/P26
972CD7453209CD74 molecule, major histocompatibility complex, class II invariant chainII, DHLAG, HLADG, Ia-GAMMA
941CD8033804CD80 moleculeB7, BB1, B7-1, B7.1, LAB7, CD28LG, CD28LG1
999CDH11620917cadherin 1, type 1UVO, CDHE, ECAD, LCAM, Arc-1, CD324
1000CDH21820424cadherin 2, type 1, N-cadherin (neuronal)CDHN, NCAD, CD325, CDw325
1022CDK751363cyclin-dependent kinase 7CAK1, HCAK, MO15, STK1, CDKN7, p39MO15
54901CDKAL169830CDK5 regulatory subunit associated protein 1-like 1
1026CDKN1A6333cyclin-dependent kinase inhibitor 1A (p21, Cip1)P21, CIP1, SDI1, WAF1, CAP20, CDKN1, MDA-6, p21CIP
1116CHI3L1155569chitinase 3-like 1 (cartilage glycoprotein-39)GP39, ASRT7, GP-39, YKL40, CGP-39, YKL-40, YYL-40,
1118CHIT1168318CHI3,CHIT,CHITDchitinase 1
1124CHN2731213chimerin 2BCH, CHN2-3, ARHGAP3, RHOGAP3
56994CHPT11269297choline phosphotransferase 1CPT, CPT1
1154CISH37667cytokine inducible SH2-containing proteinCIS, G18, SOCS, CIS-1, BACTS2
1184CLCN5X73872chloride channel, voltage-sensitive 5XRN, CLC5, XLRH, CLCK2, ClC-5, DENTS, NPHL1, NPHL2
6320CLEC11A192236C-type lectin domain family 11, member AP47, SCGF, LSLCL, CLECSF3
1215CMA11455606chymase 1, mast cellCYH, MCT1, chymase
100272147CMC4X106257C-x(9)-C motif containing 4p8, C6.1B, MTCP1, MTCP1B, MTCP1NB, p8MTCP1
84735CNDP11857178carnosine dipeptidase 1 (metallopeptidase M20 family)CN1, CPGL2, HsT2308
55748CNDP21810085CNDP dipeptidase 2 (metallopeptidase M20 family)CN2, CPGL, PEPA, HsT2298, HEL-S-13
1268CNR167273canbinoid receptor 1 (brain)CB1, CNR, CB-R, CB1A, CB1R, CANN6, CB1K5
1269CNR211389cannabinoid receptor 2 (macrophage)CB2, CX5, CB-2
1295COL8A1322423collagen, type VIII, alpha 1C3orf7
1296COL8A2155879collagen, type VIII, alpha 2FECD, PPCD, FECD1, PPCD2
54504CPVL780235carboxypeptidase, vitellogenic-likeHVLP
1398CRK1781850v-crk avian sarcoma virus CT10 oncogene homologp38, CRKII
1401CRP1128039C-reactive protein, pentraxin-relatedPTX1
1470CST22088653 cystatin SA NA
1471CST32078cystatin CARMD11, HEL-S-2
1490CTGF61431connective tissue growth factorCCN2, NOV2, HCS24, IGFBP8
8029CUBN1037434IFCR,MGA1,gp280cubilin
6376CX3CL1162251chemokine (C-X3-C motif) ligand 1NTN, NTT, CXC3, CXC3C, SCYD1, ABCD-3, C3Xkin
1524CX3CR1320350chemokine (C-X3-C motif) receptor 1V28, CCRL1, GPR13, CMKDR1, GPRV28, CMKBRL1
3627CXCL1041203chemokine (C-X-C motif) ligand 10C7, IFI10, INP10, IP-10, crg-2, mob-1, SCYB10, gIP
6373CXCL1143944chemokine (C-X-C motif) ligand 11IP9, H174, IP-9, b-R1, I-TAC, SCYB11, SCYB9B
6387CXCL1210128606chemokine (C-X-C motif) ligand 12IRH, PBSF, SDF1, TLSF, TPAR1, SCYB12
58191CXCL161749694chemokine (C-X-C motif) ligand 16SRPSOX, CXCLG16, SR-PSOX
6374CXCL5488672chemokine (C-X-C motif) ligand 5SCYB5, ENA-78
3576CXCL8447937chemokine (C-X-C motif) ligand 8IL8, F, GCP1, LECT, LUCT, P1, GCP-1, LYP,
4283CXCL941813chemokine (C-X-C motif) ligand 9CMK, MIG, Humig, SCYB9, crg-10
1535CYBA1680cytochrome b-245, alpha polypeptidep22-PHOX
1591CYP24A12068094cytochrome P450, family 24, subfamily A, polypeptide 1CP24, HCAI, CYP24, P450-CC24
1573CYP2J2168091cytochrome P450, family 2, subfamily J, polypeptide 2CPJ2
1634DCN1222430decorinCSCD, PG40, PGII, PGS2, DSPG2, SLRR1B
51181DCXR1722964dicarbonyl/L-xylulose reductaseXR, DCR, HCR2, P34H, HCRII, KIDCR, PNTSU, SDR20C1
23576DDAH118120dimethylarginine dimethylaminohydrolase 1DDAH, HEL-S-16
1649DDIT3123012DNA-damage-inducible transcript 3CHOP, CEBPZ, CHOP10, CHOP-10, GADD153
1667DEFA18128756defensin, alpha 1HP1, MRS, DEF1, HP-1, DEFA2, HNP-1
1674DES256469desminCSM1, CSM2, LGMD2R
160851DGKH1399373diacylglycerol kinase, etaDGKeta
22943DKK1107689dickkopf WNT signaling pathway inhibitor 1SK, DKK-1
1786DNMT119124071DNA (cytosine-5-)-methyltransferase 1AIM, DNMT, MCMT, CXXC9, HSN1E, ADCADN
1803DPP423279dipeptidyl-peptidase 4CD26, ADABP, ADCP2, DPPIV, TP103
92126DSEL1812964dermatan sulfate epimerase-likeC18orf4
64641EBF2856471early B-cell factor 2COE2, OE-3, EBF-2, O/E-3
1906EDN161476endothelin 1ET1, QME, PPET1, ARCND3, HDLCQ7
1909EDNRA41478endothelin receptor type AETA, ET-A, ETAR, ETRA, MFDA, ETA-R, hET-AR
1950EGF41483epidermal growth factorURG, HOMG4
1956EGFR774545epidermal growth factor receptorERBB, HER1, mENA, ERBB1, PIG61, NISBD2
9451EIF2AK323557eukaryotic translation initiation factor 2-alpha kinase 3PEK, WRS, PERK
1978EIF4EBP183021eukaryotic translation initiation factor 4E binding protein 1BP-1, 4EBP1, 4E-BP1, PHAS-I
9844ELMO1756685engulfment and cell motility 1CED12, CED-12, ELMO-1
2022ENG992endoglinEND, HHT1, ORW1
5167ENPP1638151ectonucleotide pyrophosphatase/phosphodiesterase 1M6S1, NPP1, NPPS, PC-1, PCA1, ARHR2, COLED,
953ENTPD11020423ectonucleoside triphosphate diphosphohydrolase 1CD39, SPG64, ATPDase, NTPDase-1
2056EPO7624erythropoietinEP, MVCD2
2057EPOR1995erythropoietin receptorEPO-R
2066ERBB4221084erb-b2 receptor tyrosine kinase 4HER4, ALS19, p180erbB4
2067ERCC1191501excision repair cross-complementation group 1UV20, COFS4, RAD10
2072ERCC4163836excision repair cross-complementation group 4XPF, RAD1, FANCQ, ERCC11
54206ERRFI1110344ERBB receptor feedback inhibitor 1MIG6, RALT, MIG-6, GENE-33
90952ESAM1112316endothelial cell adhesion moleculeW117m
2099ESR1647906estrogen receptor 1ER, ESR, Era, ESRA, ESTRR, NR3A1
23016EXOSC738994exosome component 7p8, EAP1, RRP42, Rrp42p, hRrp42p
7430EZR655740ezrinCVL, CVIL, VIL2, HEL-S-105
2160F11486654coagulation factor XIFXI
2149F2R51510coagulation factor II (thrombin) receptorTR, HTR, CF2R, PAR1, PAR-1
2168FABP121106fatty acid binding protein 1, liverFABPL, L-FABP
2169FABP24107fatty acid binding protein 2FABPI, I-FABP
2167FABP4836067fatty acid binding protein 4 adipocyteaP2, ALBP, AFABP, A-FABP, HEL-S-104
2194FASN1755800fatty acid synthaseFAS, OA-519, SDR27X1
26291FGF211910428fibroblast growth factor 21NONE
8074FGF231210771fibroblast growth factor 23ADHR, FGFN, HYPF, HPDR2, PHPTC
64122FN3K1723336fructosamine 3 kinaseNONE
252995FNDC5117812fibronectin type III domain containing 5FRCP2, irisin
2353FOS143844FBJ murine osteosarcoma viral oncogene homologp55, AP-1, C-FOS
2308FOXO1131527forkhead box O1FKH1, FKHR, FOXO1A
4303FOXO4X4342forkhead box O4AFX, AFX1, MLLT7
257019FRMD3916012FERM domain containing 34.1O, P410, EPB41LO, EPB41L4O
79068FTO168053fat mass and obesity associatedALKBH9
2539G6PDX37906glucose-6-phosphate dehydrogenaseG6PD1
2619GAS191548growth arrest-specific 1
2621GAS613638growth arrest specific 6AXSF, AXLLG
2641GCG2136497GLP1,GLP2,GRPPglucagon
2645GCK755440glucokinase (hexokinase 4)GK, GLK, HK4, HHF3, HKIV, HXKP, LGLK, MODY2, FGQTL
9518GDF15193576growth differentiation factor 15PDF, MIC1, PLAB, MIC-1, NAG-1, PTGFB, GDF-15
2673GFPT1268220glutamine--fructose-6-phosphate transaminase 1GFA, GFAT, GFPT, MSLG, CMS12, GFAT1, CMSTA1, GFAT,
9945GFPT2568439glutamine-fructose-6-phosphate transaminase 2GFAT2
2678GGT12268450gamma-glutamyltransferase 1GGT, GTG, CD224, GGT, 1, D22S672, D22S732
728441GGT22268450gamma-glutamyltransferase 2GGT, GGT, 2
2690GHR5134growth hormone receptorGHBP, GHIP
51738GHRL3139965ghrelin/obestatin prepropeptideMTLRP
2693GHSR357161growth hormone secretagogue receptorGHDP
2739GLO164880glyoxalase IGLYI, GLOD1, HEL-S-74
2784GNB31255628guanine nucleotide binding protein (G protein), beta polypeptide 3
2262GPC5133285glypican 5
26585GREM1158022gremlin 1, DAN family BMP antagonistDRM, HMPS, MPSH, PIG2, CRAC1, CRCS4, DAND2, HMPS1,
2944GSTM118022glutathione S-transferase mu 1MU, H-B, GST1, GTH4, GTM1, MU-1, GSTM1-1, GSTM1a-1
2950GSTP111660 glutathione S-transferase pi 1PI DFN7 GST3 GSTP FAEES3 HEL-S-22
2952GSTT122NAglutathione S-transferase theta 1
9759HDAC4255946histone deacetylase 4HD4, AHO3, BDMR, HDACA, HA6116, HDAC-4, HDAC-A
3077HFE688330hemochromatosisHH, HFE1, HLA-H, MVCD7, TFQTL2
3082HGF7503hepatocyte growth factor (hepapoietin A; scatter factor)SF, HGFB, HPTA, F-TCF, DFNB39
3087HHEX1031110hematopoietically expressed homeoboxHEX, PRH, HMPH, PRHX, HOX11L-PEN
3091HIF1A141171hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)HIF1,MOP1,PASD8,HIF-1A,bHLHe78, HIF-1alpha,HIF1-A
3105HLA-A6128352major histocompatibility complex, class I, AHLAA
3117HLA-DQA16123820major histocompatibility complex, class II, DQ alpha 1CD, GSE, DQ-A1, CELIAC1, HLA-DQA
83872HMCN1123741hemicentin 1ARMD1, FBLN6, FIBL6, FIBL-6
8091HMGA212136767high mobility group AT-hook 2BABL, LIPO, HMGIC, HMGI-C, STQTL9
3146HMGB113110676high mobility group box 1HMG1, HMG3, HMG-1, SBP-1
3158HMGCS21380663-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
3162HMOX12231075heme oxygenase 1HO-1, HSP32, HMOX1D, bK286B10
6927HNF1A12459HNF1 homeobox AHNF1, LFB1, TCF1, MODY3, TCF-1, HNF-1A, IDDM20
3240HP16121756haptoglobinBP, HPA1S, HP2ALPHA2
10855HPSE468528heparanaseHPA, HPA1, HPR1, HSE1, HPSE1
3303HSPA1A674294heat shock 70kDa protein 1AHSP72, HSPA1, HSP70I, HSP70-1, HSP70.1, HSP70-1A,
3304HSPA1B674294heat shock 70kDa protein 1BHSP70-2, HSP70.2, HSP70-1B
3315HSPB171180heat shock 27kDa protein 1CMT2F, HMN2B, HSP27, HSP28, Hsp25, SRP27, HS
3339HSPG2168473heparan sulfate proteoglycan 2PLC, SJA, SJS, HSPG, SJS1, PRCAN
3356HTR2A13684735-hydroxytryptamine (serotonin) receptor 2A, G protein-coupledHTR2, 5-HT2A
10525HYOU1114658hypoxia up-regulated 1Grp170, HSP12A, ORP150, GRP-170, ORP-150
3383ICAM119168intercellular adhesion molecule 1BB2, CD54, P3.58
3397ID120168inhibitor of DNA binding 1, dominant negative helix-loop-helix proteinID, bHLHb24
3458IFNG121631interferon, gammaIFG, IFI
3479IGF11255526insulin-like growth factor 1 (somatomedin C)MGF, IGFI, IGF-I
3480IGF1R1530997insulin like growth factor 1 receptorIGFR, CD221, IGFIR, JTK13
3481IGF211510insulin-like growth factor 2 (somatomedin A)IGF-II, PP9974, C11orf43
3484IGFBP17498insulin like growth factor binding protein 1AFBP, IBP1, PP12, IGF-BP25, hIGFBP-1
3486IGFBP37510insulin-like growth factor binding protein 3IBP3, BP-53
3490IGFBP741193AGM,PSF,TAF,FSTL2,IBP-7,MAC25,IGFBP-7,RAMSVPS,IGFBP-7v,IGFBPRP1insulin like growth factor binding protein 7
3586IL101478interleukin 10CSIF, TGIF, GVHDS, IL-10, IL10A
3605IL17A61651interleukin 17AIL17, CTLA8, IL-17, CTLA-8, IL-17A
3606IL18111200interleukin 18IGIF, IL-18, IL-1g, IL1F4
3553IL1B2481interleukin 1 betaIL-1, IL1F2, IL1-BETA
3557IL1RN211163interleukin 1 receptor antagonistDIRA, IRAP, IL1F3, IL1RA, MVCD4, IL-1RN, IL-
3569IL67502interleukin 6HGF, HSF, BSF2, IL-6, IFNB2
3611ILK113318integrin-linked kinaseP59, ILK-1, ILK-2, p59ILK, HEL-S-28
8660IRS2132778insulin receptor substrate 2IRS-2
3684ITGAM16526integrin, alpha M (complement component 3 receptor 3 subunit)CR3A, MO1A, CD11B, MAC-1, MAC1A, SLEB6
3717JAK2921033Janus kinase 2JTK10, THCYT3
221895JAZF1718291JAZF zinc finger 1TIP27, ZNF802
3784KCNQ11185014potassium channel, voltage gated KQT-like subfamily Q, member 1LQT, RWS, WRS, LQT1, SQT2, ATFB1, ATFB3, JLNS1, KC
9365KL1368415klotho
7071KLF1084135Kruppel-like factor 10EGRA, TIEG, TIEG1, EGR-alpha
1316KLF610996Kruppel-like factor 6GBF, ZF9, BCD1, CBA1, CPBP, PAC1, ST12, COP
58508KMT2C746480lysine methyltransferase 2CHALR, MLL3
3915LAMC111724laminin subunit gamma 1LAMB2
51056LAP3441072leucine aminopeptidase 3LAP, PEPS, LAPEP, HEL-S-106
3934LCN294064lipocalin 2p25, 24p3, MSFI, NGAL
3952LEP7193leptinOB, OBS, LEPD
3985LIMK22255911LIM domain kinase 2
4000LMNA141321lamin A/CFPL, IDC, LFP, CDDC, EMD2, FPLD, HGPS, LDP1, LMN1,
4023LPL8200lipoprotein lipaseLIPD, HDLCQ11
4036LRP2220952DBS,GP330LDL receptor related protein 2
4049LTA6497lymphotoxin alphaLT, TNFB, TNFSF1
10459MAD2L214624MAD2 mitotic arrest deficient-like 2 (yeast)REV7, MAD2B, POLZ2
10892MALT1184938MALT1 paracaspaseMLT, MLT1, IMD12, PCASP1
4217MAP3K5638114mitogen-activated protein kinase kinase kinase 5ASK1, MEKK5, MAPKKK5
5594MAPK12237670mitogen-activated protein kinase 1ERK, p38, p40, p41, ERK2, ERT1, ERK-2, MAPK2, PRKM
1432MAPK14631777mitogen-activated protein kinase 14RK, p38, CSBP, EXIP, Mxi2, CSBP1, CSBP2, CSPB1, PR
4153MBL210110436mannose-binding lectin (protein C) 2, solubleMBL, MBP, MBP1, MBPD, MBL2D, MBP-C, COLEC1, HSMBPC
4160MC4R184320melanocortin 4 receptor
4162MCAM114742melanoma cell adhesion moleculeCD146, MUC18
4225MEP1B1848382meprin A, beta
4282MIF2255655macrophage migration inhibitory factor (glycosylation-inhibiting factor)GIF, GLIF, MMIF
55586MIOX229732myo-inositol oxygenaseALDRL6
4323MMP141421040matrix metallopeptidase 14 (membrane-inserted)MMP-14, MMP-X1, MT-MMP, MT1MMP, MTMMP1, WNCHRS, MT
4325MMP16855939matrix metallopeptidase 16 (membrane-inserted)MMP-X2, C8orf57, MT-MMP2, MT-MMP3, MT3-MMP
4313MMP2163329matrix metallopeptidase 2 (gelatise A, 72kDa gelatise, 72kDa type IV collagese)CLG4, MO, CLG4A, TBE-1, MMP-II
9518MMP242021331MMP25 MMP-24 MT5MMP MTMMP5 MT-MMP5 MT5-MMP MT-MMP 5
4318MMP9203659matrix metallopeptidase 9 (gelatise B 92kDa gelatise 92kDa type IV collagese)GELB, CLG4B, MMP-9, MANDP2
2837MOK148062MOK protein kinaseRAGE, RAGE1, STK30, RAGE-1
4353MPO1755450myeloperoxidase
4524MTHFR14349methylenetetrahydrofolate reductase (D(P)H)
2475MTOR13637mechanistic target of rapamycin (serine/threonine kinase)FRAP, FRAP1, FRAP2, RAFT1, RAPT1
4615MYD8831849MYD88Dmyeloid differentiation primary response 88
4627MYH922129835myosin, heavy chain 9, non-muscleMHA, FTNS, EPSTS, BDPLT6, DFNA17, NMMHCA, NMHC-II-
83988NCALD849978neurocalcin delta
653361NCF1124491nuclear factor, erythroid 2p45, NF-E2
4688NCF222412nuclear factor, erythroid 2-like 2NRF2, HEBP1
4722NDUFS3124491nuclear factor, erythroid 2p45, NF-E2
23327NEDD4L22412nuclear factor, erythroid 2-like 2NRF2, HEBP1
4778NFE2124491nuclear factor, erythroid 2p45, NF-E2
4780NFE2L222412nuclear factor, erythroid 2-like 2NRF2, HEBP1
4790NFKB142971nuclear factor kappa B subunit 1p50 KBF1 p105 EBP-1 CVID12 NF-kB1 NFKB-p50 NFkappa
4792NFKBIA147863NFKB inhibitor alphaIKBA, MAD-3, NFKBI
4803NGF11876nerve growth factor (beta polypeptide)NGFB, HSAN5, Beta-NGF
114548NLRP313600NLR family, pyrin domain containing 3AII, AVP, FCU, MWS, FCAS, CIAS1, FCAS1, NALP3, C1o
64127NOD21611156nucleotide-binding oligomerization domain containing 2CD, ACUG, BLAU, IBD1, NLRC2, NOD2B, CARD15, CLR16.
4842NOS11237327nitric oxide synthase 1 (neuronal)NOS, bNOS, nNOS, IHPS1, N-NOS, NC-NOS
4843NOS21755473nitric oxide synthase 2NOS, INOS, NOS2A, HEP-NOS
4846NOS37504nitric oxide synthase 3 (endothelial cell)eNOS, ECNOS
4856NOV81884nephroblastoma overexpressedCCN3, NOVh, IBP-9, IGFBP9, IGFBP-9
27035NOX1X48495DPH oxidase 1MOX1, NOH1, NOH-1, GP91-2
50508NOX3649435DPH oxidase 3MOX-2, GP91-3
50507NOX41141065NADPH oxidase 4KOX, KOX-1, RENOX
4868NPHS11920974nephrosis 1, congenital, Finnish type (nephrin)CNF, NPHN, nephrin
4852NPY7697neuropeptide YPYY4
10062NR1H31121165nuclear receptor subfamily 1, group H, member 3LXRA, LXR-a, RLD-1
10412NSA255844NSA2 ribosome biogenesis homolog (S. cerevisiae)HCLG1, TINP1, CDK105, HCL-G1, HUSSY29, HUSSY-29
3175ONECUT1153309one cut homeobox 1HNF6, HNF-6, HNF6A
5008OSM2210741oncostatin M
55486PARL310239presenilin associated, rhomboid-likePSARL, PSARL1, RHBDS1, PRO2207, PSENIP2
5073PARN1631098 poly(A)-specific ribonuclease DAN, DKCB6, PFBMFT4
142PARP111222poly (ADP-ribose) polymerase 1PARP, PPOL, ADPRT, ARTD1, ADPRT1, PARP-1, ADPRT, 1
5091PC11pyruvate carboxylasePCB
8654PDE5A4842phosphodiesterase 5A, cGMP-specificCN5A, PDE5, CGB-PDE
5154PDGFA732055platelet-derived growth factor alpha polypeptidePDGF1, PDGF-A
5155PDGFB2274303platelet-derived growth factor beta polypeptideSIS, SSV, IBGC5, PDGF2, c-sis, PDGF-2
5159PDGFRB51960platelet-derived growth factor receptor, beta polypeptideIMF1, IBGC4, JTK12, PDGFR, CD140B, PDGFR1, P
5163PDK12134437pyruvate dehydrogenase kinase 1
5170PDPK116376433-phosphoinositide dependent protein kinase 1PDK1, PDPK2, PDPK2P, PRO0461
5037PEBP11237637phosphatidylethanolamine binding protein 1PBP, HCNP, PEBP, RKIP, HCNPpp, PEBP-1, HEL-210, HE
5208PFKFB21885546-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2PFK-2/FBPase-2
9463PICK1227470protein interacting with PRKCA 1PICK, PRKCABP
5290PIK3CA321249phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alphaMCM, CWS5, MCAP, PI3K, CLOVE, MCMTC, p110-alpha
5304PIP71990prolactin induced proteinGPIP4, GCDFP15, GCDFP-15
130271PLEKHH2235317pleckstrin homology domain containing, family H (with MyTH4 domain) member 2PLEKHH1L
127435PODN117803podocanPCAN, SLRR5A
5444PON1768058paraoxose 1ESA, PON, MVCD5
5445PON27385paraoxose 2
10631POSTN134730periostin, osteoblast specific factorPN, OSF2, OSF-2, PDLPOSTN
5465PPARA2221047peroxisome proliferator activated receptor alphaPPAR, NR1C1, hPPAR, PPARalpha
5468PPARG37899peroxisome proliferator-activated receptor gammaGLM1, CIMT1, NR1C3, PPARG1, PPARG2, PPARgamma
10891PPARGC1A47485peroxisome proliferator-activated receptor gamma, coactivator 1 alphaLEM6, PGC1, PGC1A, PGC-1v, PPARGC1, PGC-1(alp
5478PPIA7134504CYPA,CYPH,HEL-S-69ppeptidylprolyl isomerase A
5547PRCP1155867prolylcarboxypeptidasePCP, HUMPCP
5562PRKAA1549590protein kinase, AMP-activated, alpha 1 catalytic subunitAMPK, AMPKa1
5563PRKAA214551protein kinase AMP-activated catalytic subunit alpha 2AMPK, AMPK2, PRKAA, AMPKa2
5579PRKCB1656424protein kinase C betaPKCB, PRKCB1, PRKCB2, PKC-beta
5581PRKCE248343protein kinase C, epsilonPKCE, nPKC-epsilon
5624PROC237288protein C (inactivator of coagulation factors Va and VIIIa)PC, APC, PROC1, THPH3, THPH4
5687PSMA6142085proteasome (prosome, macropain) subunit, alpha type, 6IOTA, p27K, PROS27
5715PSMD9122106proteasome (prosome, macropain) 26S subunit, non-ATPase, 9p27,Rpn4
5728PTEN10265phosphatase and tensin homologBZS, DEC, CWS1, GLM2, MHAM, TEP1, MMAC1, PT
5730PTGDS9737prostaglandin D2 synthase 21kDa (brain)PDS, PGD2, PGDS, LPGDS, PGDS2, L-PGDS
5731PTGER119738prostaglandin E receptor 1 (subtype EP1), 42kDaEP1
5734PTGER4520261prostaglandin E receptor 4 (subtype EP4)EP4, EP4R
9536PTGES93587prostaglandin E synthasePGES, MPGES, PIG12, PP102, PP1294, MGST-IV, MGST1L
5743PTGS2131000prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)COX2, COX-2, PHS-2, PGG/HS, PGHS-2, hCox-2, GRIPGH
5741PTH11266parathyroid hormonePTH1
5745PTH1R3267parathyroid hormone 1 receptorPFE, PTHR, PTHR1
5770PTPN1202119protein tyrosine phosphatase, non-receptor type 1PTP1B
5806PTX337500pentraxin 3, longTSG-14, TNFAIP5
5820PVT18Pvt1 oncogene (non-protein coding)LINC00079, NCR00079
5894RAF1348145Raf-1 proto-oncogene, serine/threonine kinaseNS5, CRAF, Raf-1, c-Raf, CMD1NN
5950RBP4104908retinol binding protein 4, plasmaRDCCAS, MCOPCB10
1827RCAN1213251regulator of calcineurin 1CSP1, DSC1, RCN1, DSCR1, MCIP1, ADAPT78
5967REG1A268282regenerating islet-derived 1 alphaP19, PSP, PTP, REG, ICRF, PSPS, PSPS1
5970RELA1132064v-rel avian reticuloendotheliosis viral oncogene homolog Ap65, NFKB3
56729RETN1910703resistinNA
9104RGNX3437regucalcinRC, GNL, SMP30, HEL-S-41
29984RHOD1122409ras homolog family member DRho, ARHD, RHOM, RHOHP1
6093ROCK11855899Rho-associated, coiled-coil containing protein kinase 1ROCK-I, P160ROCK
6206RPS126110750ribosomal protein S12S12
6194RPS6985949ribosomal protein S6S6
6239RREB162218ras responsive element binding protein 1HNT, FINB, LZ321, Zep-1, RREB-1
6252RTN11449654reticulon 1NSP
6287SAA@11serum amyloid A1 clusterSAA, SAA4
6288SAA111128033serum amyloid A1SAA, PIG4, SAA2, TP53I4
642658SCX885195scleraxis bHLH transcription factorSCXA, SCXB, bHLHa48
6401SELE1389selectin EELAM, ESEL, CD62E, ELAM1, LECAM2
10371SEMA3A731358sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3AHH16, SemD, COLL1, SEMA1, SEMAD, SEMAL, coll-1, Hs
8710SERPINB71868363serpin peptidase inhibitor, clade B (ovalbumin), member 7PPKN, TP55, MEGSIN
5054SERPINE1768070serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1PAI, PAI1, PAI-1, PLANH1
5176SERPINF1171965serpin family F member 1OI6, OI12, PEDF, EPC-1, PIG35
5345SERPINF217719serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2AAP, API, PLI, A2AP, ALPHA-2-PI
80854SETD7412741SET domain containing (lysine methyltransferase) 7KMT7, SET7, SET9, SET7/9
9814SFI12212707Sfi1 homolog, spindle assembly associated (yeast)PISD, hSfi1p, PPP1R139
6446SGK1648364serum/glucocorticoid regulated kinase 1SGK
10110SGK2208446serum/glucocorticoid regulated kinase 2H-SGK2, dJ138B7.2
23678SGK3856582serum/glucocorticoid regulated kinase family, member 3CISK, SGK2, SGKL
6614SIGLEC120124458sialic acid binding Ig-like lectin 1, sialoadhesinSN, CD169, SIGLEC-1, dJ1009E24.1
23411SIRT11056556sirtuin 1SIR2, SIR2L1, SIR2alpha
51548SIRT6196924sirtuin 6SIR2L6
6559SLC12A316287solute carrier family 12 (sodium/chloride transporter), member 3NCC, TSC, NCCT
9356SLC22A61116813solute carrier family 22 (organic anion transporter), member 6OAT1, PAHT, HOAT1, ROAT1
6513SLC2A1168520solute carrier family 2 (facilitated glucose transporter), member 1CSE, PED, DYT9, GLUT, DYT17, DYT18, EIG12, GLUT1,
6514SLC2A2368047solute carrier family 2 member 2GLUT2
6517SLC2A41774381solute carrier family 2 member 4GLUT4
169026SLC30A8813795solute carrier family 30 (zinc transporter), member 8ZNT8, ZnT-8
6548SLC9A1120660solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1APNH, NHE1, LIKNS, NHE-1, PPP1R143
4086SMAD1421196SMAD family member 1BSP1, JV41, BSP-1, JV4-1, MADH1, MADR1
4092SMAD7184314SMAD family member 7CRCS3, MADH7, MADH8
8651SOCS1162776suppressor of cytokine signaling 1JAB, CIS1, SSI1, TIP3, CISH1, SSI-1, SOCS-1
8835SOCS2122880suppressor of cytokine signaling 2CIS2, SSI2, Cish2, SSI-2, SOCS-2, STATI2
9021SOCS3172941suppressor of cytokine signaling 3CIS3, SSI3, ATOD4, Cish3, SSI-3, SOCS-3
6647SOD121392superoxide dismutase 1, solubleALS, SOD, ALS1, IPOA, hSod1, HEL-S-44, homodimer
6648SOD26530superoxide dismutase 2, mitochondrialIPOB, MNSOD, MVCD6
8470SORBS2483295sorbin and SH3 domain containing 2ARGBP2, PRO0618
50964SOST1711542sclerostinCDD, VBCH, SOST1
6662SOX917294SRY (sex determining region Y)-box 9CMD1, SRA1, CMPD1
6678SPARC531132secreted protein, acidic, cysteine-rich (osteonectin)ON, BM-40
10417SPON2440843spondin 2, extracellular matrix proteinDIL1, DIL-1, MINDIN, M-SPONDIN
6696SPP1420156secreted phosphoprotein 1OPN, BNSP, BSPI, ETA-1
6714SRC2021120SRC proto-oncogene, non-receptor tyrosine kinaseASV, SRC1, c-SRC, p60-Src
6720SREBF1173079sterol regulatory element binding transcription factor 1SREBP1, bHLHd1, SREBP-1c
6750SST3819somatostatinSMST
6772STAT1221428signal transducer and activator of transcription 1, 91kDaCANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT91
6774STAT3177960signal transducer and activator of transcription 3 (acute-phase response factor)APRF, HIES, ADMIO
6776STAT5A1720680signal transducer and activator of transcription 5AMGF, STAT5
246744STH1788448saitohinMAPTIT
6794STK1119393serine/threonine kinase 11PJS, LKB1, hLKB1
56670SUCNR1341865succinate receptor 1GPR91
387082SUMO4688399small ubiquitin-like modifier 4IDDM5, SMT3H4, SUMO-4, dJ281H8.4
6934TCF7L2107564transcription factor 7-like 2 (T-cell specific, HMG-box)TCF4, TCF-4
7018TF368153transferrinTFQTL1, PRO1557, PRO2086
7040TGFB119540transforming growth factor, beta 1CED, LAP, DPD1, TGFB, TGFbeta
7046TGFBR193177transforming growth factor beta receptor IAAT5, ALK5, ESS1, LDS1, MSSE, SKR4, ALK-5, LDS1A,
7056THBD20308thrombomodulinTM, THRM, AHUS6, BDCA3, CD141, THPH12
7057THBS11531142thrombospondin 1TSP, THBS, TSP1, TSP-1, THBS-1
7058THBS262438thrombospondin 2TSP2
10469TIMM44194631translocase of inner mitochondrial membrane 44 homolog (yeast)TIM44
7076TIMP1X36321TIMP metallopeptidase inhibitor 1EPA, EPO, HCI, CLGI, TIMP
7077TIMP2172444TIMP metallopeptidase inhibitor 2DDC8, CSC-21K
7078TIMP32236322TIMP metallopeptidase inhibitor 3SFD, K222, K222TA2, HSMRK222
7086TKT368154transketolaseTK, TKT1, HEL107
7097TLR2420695toll-like receptor 2TIL4, CD282
7099TLR4941317toll-like receptor 4TOLL, CD284, TLR-4, ARMD10
7124TNF6496tumor necrosis factorDIF, TNFA, TNFSF2, TNLG1F, TNF-alpha
25816TNFAIP858649tumor necrosis factor, alpha-induced protein 8NDED, GG2-1, SCCS2, SCC-S2, MDC-3.13
4982TNFRSF11B81912tumor necrosis factor receptor superfamily member 11bOPG, TR1, OCIF, PDB5
7132TNFRSF1A12828TNF receptor superfamily member 1AFPF, p55, p60, TBP1, TNF-R, TNFAR, TNFR1, p55-R, C
57761TRIB32010902tribbles pseudokinase 3NIPK, SINK, TRB3, SKIP3, C20orf97
7220TRPC132478transient receptor potential cation channel, subfamily C, member 1TRP1, HTRP-1
7225TRPC61137944transient receptor potential cation channel subfamily C member 6TRP6, FSGS2
59341TRPV41211003transient receptor potential cation channel, subfamily V, member 4SMAL, VRL2, BCYM3, CMT2C, SPSMA, TRP12, VROA
7248TSC19314tuberous sclerosis 1LAM, TSC
7249TSC216462tuberous sclerosis 2LAM, TSC4, PPP1R160
8848TSC22D1137573TSC22 domain family member 1Ptg-2, TSC22, TGFB1I4
10628TXNIP138186thioredoxin interacting proteinTHIF, VDUP1, HHCPA78, EST01027
7351UCP2112516uncoupling protein 2 (mitochondrial proton carrier)UCPH, BMIQ4, SLC25A8
29128UHRF1197866ubiquitin-like with PHD and ring finger domains 1Np95, hNP95, ICBP90, RNF106, hUHRF1, huNp95
7369UMOD162522uromodulinTHP, FJHN, HNFJ, THGP, HNFJ1, MCKD2, ADMCKD2
10497UNC13B931376unc-13 homolog B (C. elegans)UNC13, MUNC13, Unc13h2
219699UNC5B1032538unc-5 netrin receptor BUNC5H2, p53RDL1
7392USF2192527upstream transcription factor 2, c-fos interactingFIP, bHLHb12
7402UTRN621398utrophinDRP, DMDL, DRP1
10893UTS2R1710345urotensin 2 receptorUTR, UTR2, GPR14, UR-2-R
7416VDAC15107244voltage dependent anion channel 1PORIN, VDAC-1
7417VDAC21037765voltage dependent anion channel 2POR
7421VDR1237297vitamin D (1,25- dihydroxyvitamin D3) receptorNR1I1, PPP1R163
7422VEGFA62534vascular endothelial growth factor AVPF, VEGF, MVCD1
7450VWF12466von Willebrand factorVWD, F8VWF
7466WFS144380Wolfram syndrome 1 (wolframin)WFS, WFRS, WFSL, CTRCT41
7490WT11111536Wilms tumor 1GUD, AWT1, WAGR, WT33, NPHS4, WIT-2, EWS-WT1
7494XBP1223722X-box binding protein 1XBP2, TREB5, XBP-1, TREB-5
7515XRCC11931368X-ray repair cross complementing 1RCC, SCAR26
7517XRCC31436178 X-ray repair cross complementing 3 CMM6
9839ZEB228868zinc finger E-box binding homeobox 2SIP1, SIP-1, ZFHX1B, HSPC082, SMADIP1
7776ZNF236187198zinc finger protein 236ZNF236A, ZNF236B