| VIP |
| LOCUS ID | 7432 | ||||||
| GENE_SYMBOL | VIP | ||||||
| GENE NAME | vasoactive intestil peptide | ||||||
| SYNONYMNS | PHM27 | ||||||
| CHROMOSOME | 6 | ||||||
| HOMOLOGENE ID | 2539 | ||||||
| SOURCE | RATS |
| PMIDs | 24370785 |
| GENE SUMMARY |
|---|
| The protein encoded by this gene belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. Altertive splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008] |
| OBSERVATION |
|---|
| 1. The increase in VIP-expressing neurons was prevented in the submucosal plexus in the DG and DGT groups (p < 0.05). Supplementation with L-glutathione exerted a better neuroprotective effect than L-glutamine and may prevent the development of enteric diabetic neuropathy. |