| HNF4A |
| LOCUS ID | 3172 |
| GENE_SYMBOL | HNF4A |
| GENE NAME | hepatocyte nuclear factor 4, alpha |
| SYNONYMNS | TCF, HNF4, MODY, FRTS4, MODY1, NR2A1, TCF14, |
| CHROMOSOME | 20 |
| HOMOLOGENE ID | 395 |
| GENE SUMMARY |
|---|
| The protein encoded by this gene is a nuclear transcription factor which binds D as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012] |
| HNF4A |
| LOCUS ID | 3172 |
| GENE_SYMBOL | HNF4A |
| GENE NAME | hepatocyte nuclear factor 4, alpha |
| SYNONYMNS | TCF, HNF4, MODY, FRTS4, MODY1, NR2A1, TCF14, |
| CHROMOSOME | 20 |
| HOMOLOGENE ID | 395 |
| GENE SUMMARY |
|---|
| The protein encoded by this gene is a nuclear transcription factor which binds D as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012] |