IAPP
LOCUS ID3375
GENE_SYMBOLIAPP
GENE NAMEislet amyloid polypeptide
SYNONYMNSDAP,IAP
CHROMOSOME12
HOMOLOGENE ID36024
GENE SUMMARY
This gene encodes a member of the calcitonin family of peptide hormones. This hormone is released from pancreatic beta cells following food intake to regulate blood glucose levels and act as a satiation signal. Human patients with type 1 and advanced type 2 diabetes exhibit reduced levels of the encoded hormone in blood and pancreas. This protein also exhibits a bactericidal, antimicrobial activity. [provided by RefSeq, Jul 2016]