| PON1 |
| LOCUS ID | 5444 |
| GENE_SYMBOL | PON1 |
| GENE NAME | paraoxose 1 |
| SYNONYMNS | ESA, PON, MVCD5 |
| CHROMOSOME | 7 |
| HOMOLOGENE ID | 68058 |
| GENE SUMMARY |
|---|
| The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in corory artery disease. The gene is found in a cluster of three related paraoxose genes at 7q21.3. [provided by RefSeq, Oct 2008] |