PPP1R3A
LOCUS ID5506
GENE_SYMBOLPPP1R3A
GENE NAMEprotein phosphatase 1 regulatory subunit 3A
SYNONYMNSGM, PP1G, PPP1R3
CHROMOSOME7
HOMOLOGENE ID
GENE SUMMARY
The glycogen-associated form of protein phosphatase-1 (PP1) derived from skeletal muscle is a heterodimer composed of a 37-kD catalytic subunit and a 124-kD targeting and regulatory subunit. This gene encodes the regulatory subunit which binds to muscle glycogen with high affinity, thereby enhancing dephosphorylation of glycogen-bound substrates for PP1 such as glycogen synthase and glycogen phosphorylase kinase.