SAC
LOCUS ID55811
GENE_SYMBOLSAC
GENE NAMEadenylate cyclase 10, soluble
SYNONYMNSSAC,HCA2,SACI,Sacy,hsAC,HEL-S-7a
CHROMOSOME1
HOMOLOGENE ID10188
GENE SUMMARY
The protein encoded by this gene belongs to a distinct class of adenylyl cyclases that is soluble and insensitive to G protein or forskolin regulation. Activity of this protein is regulated by bicarbonate. Variation at this gene has been observed in patients with absorptive hypercalciuria. Alternatively spliced transcript variants encoding different isoforms have been observed. There is a pseudogene of this gene on chromosome 6. [provided by RefSeq, Jul 2014]