SYK
LOCUS ID6850
GENE_SYMBOLSYK
GENE NAMEspleen associated tyrosine kinase
SYNONYMNSp72-Syk
CHROMOSOME9
HOMOLOGENE ID2390
GENE SUMMARY
This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]