TCF7L2
LOCUS ID6934
GENE_SYMBOLTCF7L2
GENE NAMEtranscription factor 7-like 2 (T-cell specific, HM
SYNONYMNSTCF4, TCF-4
CHROMOSOME10
HOMOLOGENE ID7564
GENE SUMMARY
This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt sigling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.[provided by RefSeq, Oct 2010]