ZPR1
LOCUS ID8882
GENE_SYMBOLZPR1
GENE NAMEZPR1 zinc finger
SYNONYMNSZNF259
CHROMOSOME11
HOMOLOGENE ID2900
GENE SUMMARY
The protein encoded by this gene is found in the cytoplasm of quiescent cells but translocates to the nucleolus in proliferating cells. The encoded protein interacts with survival motor neuron protein (SMN1) to enhance pre-mRNA splicing and to induce neuronal differentiation and axonal growth. Defects in this gene or the SMN1 gene can cause spinal muscular atrophy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]