DPP4
LOCUS ID1803
GENE_SYMBOLDPP4
GENE NAMEdipeptidyl-peptidase 4
SYNONYMNSCD26, ADABP, ADCP2, DPPIV, TP103
CHROMOSOME2
HOMOLOGENE ID3279
DiseaseType 2 diabetes
PMIDs25780477
GENE SUMMARY
The protein encoded by this gene is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. [provided by RefSeq, Jul 2008]

OBSERVATIONS
dipeptidyl peptidase 4 (DPP4) inhibitors have become standard therapeutic agents for type 2 diabetes, and numbers of patients receiving insulin therapy combined with DPP4 inhibitors, which is a highly effective regimen, are increasing