FFAR1
LOCUS ID2864
GENE_SYMBOLFFAR1
GENE NAMEfree fatty acid receptor 1
SYNONYMNSFFA1R, GPR40, GPCR40
CHROMOSOME19
HOMOLOGENE ID3876
DiseaseType 2 diabetes
PMIDs25604916
GENE SUMMARY
This gene encodes a member of the GP40 family of G protein-coupled receptors that are clustered together on chromosome 19. The encoded protein is a receptor for medium and long chain free fatty acids and may be involved in the metabolic regulation of insulin secretion. Polymorphisms in this gene may be associated with type 2 diabetes. [provided by RefSeq, Apr 2009]

OBSERVATIONS
The free fatty acid receptor GPR40 has been proposed as a potential target for type 2 diabetes (T2D) pharmacotherapy.