GPR119
LOCUS ID139760
GENE_SYMBOLGPR119
GENE NAMEG protein-coupled receptor 119
SYNONYMNSGPCR2
CHROMOSOMEX
HOMOLOGENE ID18670
DiseaseType 2 Diabetes
PMIDs23897163
GENE SUMMARY
This gene encodes a member of the rhodopsin subfamily of G-protein-coupled receptors that is expressed in the pancreas and gastrointestinal tract. The encoded protein is activated by lipid amides including lysophosphatidylcholine and oleoylethanolamide and may be involved in glucose homeostasis. This protein is a potential drug target in the treatment of type 2 diabetes.[provided by RefSeq, Jan 2010]

OBSERVATIONS
Recently, G protein-coupled receptor 119 (GPR119) has been identified as a promising anti-diabetic therapeutic target