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ADIPOR2 |
LOCUS ID | 79602 | ||||||||||
GENE_SYMBOL | ADIPOR2 | ||||||||||
GENE NAME | adiponectin receptor | ||||||||||
SYNONYMNS | PAQR2 ACDCR2 | ||||||||||
CHROMOSOME | 12 | ||||||||||
HOMOLOGENE ID | 56119 |
microRNAs | NA | NA |
GENE SUMMARY |
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The adiponectin receptors, ADIPOR1 (MIM 607945) and ADIPOR2, serve as receptors for globular and full-length adiponectin (MIM 605441) and mediate increased AMPK (see MIM 602739) and PPAR-alpha (PPARA; MIM 170998) ligand activities, as well as fatty acid oxidation and glucose uptake by adiponectin (Yamauchi et al., 2003 [PubMed 12802337]).[supplied by OMIM, Mar 2008] |
OBSERVATIONS |
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Complication | Evidence | PMID |
Cardiovascular | 1. Polymorphisms of the ADIPOR2 gene are frequently linked to a higher risk of developing diseases including obesity, type 2 diabetes and cardiovascular diseases. | 28359874 |