ADIPOR2
LOCUS ID79602
GENE_SYMBOLADIPOR2
GENE NAMEadiponectin receptor
SYNONYMNSPAQR2 ACDCR2
CHROMOSOME12
HOMOLOGENE ID56119
microRNAsNANA
GENE SUMMARY
The adiponectin receptors, ADIPOR1 (MIM 607945) and ADIPOR2, serve as receptors for globular and full-length adiponectin (MIM 605441) and mediate increased AMPK (see MIM 602739) and PPAR-alpha (PPARA; MIM 170998) ligand activities, as well as fatty acid oxidation and glucose uptake by adiponectin (Yamauchi et al., 2003 [PubMed 12802337]).[supplied by OMIM, Mar 2008]

OBSERVATIONS

Complication Evidence PMID
Cardiovascular1. Polymorphisms of the ADIPOR2 gene are frequently linked to a higher risk of developing diseases including obesity, type 2 diabetes and cardiovascular diseases.28359874