| ADRA2B |
| LOCUS ID | 151 | ||||||||||
| GENE_SYMBOL | ADRA2B | ||||||||||
| GENE NAME | adrenoceptor alpha 2 | ||||||||||
| SYNONYMNS | FAME2, ADRA2L1, ADRARL1, ADRA2RL1, ALPHA2BAR, alpha-2BAR | ||||||||||
| CHROMOSOME | 2 | ||||||||||
| HOMOLOGENE ID | 553 |
| microRNAs | NA | NA |
| GENE SUMMARY |
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| This intronless gene encodes a seven-pass transmembrane protein. This protein is a member of a subfamily of G protein-coupled receptors that regulate neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. [provided by RefSeq, Apr 2014] |
| OBSERVATIONS |
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| Complication | Evidence | PMID |
| Neuropathy | 1. The aim of the present study was to investigate the potential association between alpha2B gene I/D polymorphism and peripheral neuropathy in Greek patients with type 2 diabetes mellitus.Patients with neuropathy exhibit a significantly higher frequency of the D allele in comparison to those without neuropathy | 17516297 |