ADRA2B
LOCUS ID151
GENE_SYMBOLADRA2B
GENE NAMEadrenoceptor alpha 2B
SYNONYMNSFAME2, ADRA2L1, ADRARL1, ADRA2RL1, ALPHA2BAR, alpha-2BAR
CHROMOSOME2
HOMOLOGENE ID553
microRNAsNANA
GENE SUMMARY
This intronless gene encodes a seven-pass transmembrane protein. This protein is a member of a subfamily of G protein-coupled receptors that regulate neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. [provided by RefSeq, Apr 2014]

OBSERVATIONS

Complication Evidence PMID
Neuropathy1. The aim of the present study was to investigate the potential association between alpha2B gene I/D polymorphism and peripheral neuropathy in Greek patients with type 2 diabetes mellitus.Patients with neuropathy exhibit a significantly higher frequency of the D allele in comparison to those without neuropathy17516297