AHRR
LOCUS ID57491
GENE_SYMBOLAHRR
GENE NAMEaryl-hydrocarbon receptor repressor
SYNONYMNSAHH, AHHR, bHLHe77
CHROMOSOME5
HOMOLOGENE ID49215
microRNAsNANA
GENE SUMMARY
The protein encoded by this gene participates in the aryl hydrocarbon receptor (AhR) signaling cascade, which mediates dioxin toxicity, and is involved in regulation of cell growth and differentiation. It functions as a feedback modulator by repressing AhR-dependent gene expression. Altertively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2011]

OBSERVATIONS

Complication Evidence PMID
Retinopathy1. We identified differential D methylation of 349 CpG sites representing 233 unique genes including TNF, CHI3L1 (also known as YKL-40), CHN2, GIPR, GLRA1, GPX1, AHRR, and BCOR in cases with PDR compared with controls.26248552