ALCAM
LOCUS ID214
GENE_SYMBOLALCAM
GENE NAMEactivated leukocyte cell adhesion molecule
SYNONYMNSMEMD, CD166
CHROMOSOME3
HOMOLOGENE ID1229
microRNAsNANA
GENE SUMMARY
This gene encodes a water channel protein located in the kidney collecting tubule. It belongs to the MIP/aquaporin family, some members of which are clustered together on chromosome 12q13. Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus. [provided by RefSeq, Oct 2008]

OBSERVATIONS

Complication Evidence PMID
Nephropathy1. ALCAM a novel biomarker in patients with type 2 diabetes mellitus complicated with diabetic nephropathy. Expression of ALCAM and S100B in kidney histology from patients with DN was determined by immunohistochemistry. 28325697