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APOH |
LOCUS ID | 350 | ||||||||||
GENE_SYMBOL | APOH | ||||||||||
GENE NAME | apolipoprotein H (be | ||||||||||
SYNONYMNS | BG, B2G1, B2GP1 | ||||||||||
CHROMOSOME | 17 | ||||||||||
HOMOLOGENE ID | 26 |
microRNAs | NA | NA |
GENE SUMMARY |
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This gene is expressed in adipose tissue exclusively. It encodes a protein with similarity to collagens X and VIII and complement factor C1q. The encoded protein circulates in the plasma and is involved with metabolic and hormol processes. Mutations in this gene are associated with adiponectin deficiency. Multiple altertively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Apr 2010] |
OBSERVATIONS |
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Complication | Evidence | PMID |
Cardiovascular | 1. APOH plasma concentrations are strongly associated to metabolic syndrome (MS) alterations and vascular disease in type 2 diabetic patients and could be considered as a clinical marker of cardiovascular risk | 19878946 |