AQP2
LOCUS ID359
GENE_SYMBOLAQP2
GENE NAMEaquaporin 2
SYNONYMNSAQP-CD, WCH-CD
CHROMOSOME12
HOMOLOGENE ID20137
microRNAsNANA
GENE SUMMARY
This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2011]

OBSERVATIONS

Complication Evidence PMID
Nephropathy1. Taken together, these data suggest a possible use of AQP5 and AQP2 as novel noninvasive biomarkers to help in classifying the clinical stage of DN. DOI: 10.1155/2017/4360357 PMCID: PMC5299189 28246612