BAAT
LOCUS ID570
GENE_SYMBOLBAAT
GENE NAMEbile acid-CoA:amino
SYNONYMNSBAT, BACAT
CHROMOSOME9
HOMOLOGENE ID1286
microRNAsmiR-32826900752
GENE SUMMARY
The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestil tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding the same protein have been found for th

OBSERVATIONS

Complication Evidence PMID
Atherosclerosis1. Moreover, due to its ability to oxidize glucose and lipids, BAT activation has been considered a potential therapy to combat type 2 diabetes and atherogenesis.26227180