CAMP
LOCUS ID820
GENE_SYMBOLCAMP
GENE NAMEcathelicidin antimicrobial peptide
SYNONYMNSLL37, CAP18, CRAMP, HSD26, CAP-18, FALL39, FALL-39
CHROMOSOME3
HOMOLOGENE ID110678
microRNAsNANA
GENE SUMMARY
This gene encodes a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is produced by extracellular proteolysis from the C-terminus. In addition to its antibacterial, antifungal, and antiviral activities, the encoded protein functions in cell chemotaxis, immune mediator induction, and inflammatory response regulation. [provided by RefSeq, Sep 2014]

OBSERVATIONS

Complication Evidence PMID
Tuberculosis1. CAMP gene expression was analyzed by RT-qPCR, greater fold changes were seen only in PTB group; some of these patients reach fold changes of 80, showing statistical significance when these were compared with those in the LTB group (p 0.01. These results may suggest that these antimicrobial peptides, mainly cathelicidin, could be used as a biomarker to indicate TB progression in both DM2 and NoDM2 patients.21539878