| CD28 |
| LOCUS ID | 940 | ||||||||||
| GENE_SYMBOL | CD28 | ||||||||||
| GENE NAME | CD28 molecule | ||||||||||
| SYNONYMNS | Tp44 | ||||||||||
| CHROMOSOME | 2 | ||||||||||
| HOMOLOGENE ID | 4473 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Tuberculosis | 1. Two genes, HK2 and CD28, emerged as potential culprits in diabetes-increased TB susceptibility. | 22230325 |