| CD63 |
| LOCUS ID | 967 | ||||||||||
| GENE_SYMBOL | CD63 | ||||||||||
| GENE NAME | CD63 molecule | ||||||||||
| SYNONYMNS | MLA1, ME491, LAMP-3, OMA81H, TSPAN30 | ||||||||||
| CHROMOSOME | 12 | ||||||||||
| HOMOLOGENE ID | 37526 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Nephropathy | 1. Concentrations of sE-selectin were higher in Type II diabetes patients than in control subjects, and correlated with MDMP, PDMP, plt-CD62P, and plt-CD63 levels in nephropathy patients. | 12032632 |