CNDP2
LOCUS ID55748
GENE_SYMBOLCNDP2
GENE NAMECNDP dipeptidase 2 (
SYNONYMNSCN2, CPGL, PEPA, HsT2298, HEL-S-13
CHROMOSOME18
HOMOLOGENE ID10085
microRNAsNANA
GENE SUMMARY
CNDP2, also known as tissue carnosise and peptidase A (EC 3.4.13.18), is a nonspecific dipeptidase rather than a selective carnosise (Teufel et al., 2003 [PubMed 12473676]).[supplied by OMIM, Mar 2008]

OBSERVATIONS

Complication Evidence PMID
Nephropathy1. Haplotype including these SNPs (C-C-G) was associated with a threefold increased risk of diabetic nephropathy (OR 2. 98, 95% CI 2. 43-3. 67, p < 0.0001). These data suggest that common variants in CNDP1 and CNDP2 play a role in susceptibility to kidney disease in patients with type 2 diabetes.21573905