DSEL
LOCUS ID92126
GENE_SYMBOLDSEL
GENE NAMEdermatan sulfate epi
SYNONYMNSC18orf4
CHROMOSOME18
HOMOLOGENE ID12964
microRNAsNANA
GENE SUMMARY
DSEL (Dermatan Sulfate Epimerase Like) is a Protein Coding gene. Diseases associated with DSEL include Ehlers-Danlos Syndrome, Musculocontractural Type, 2 and Temtamy Preaxial Brachydactyly Syndrome. Among its related pathways are Glycosaminoglycan metabolism and Chondroitin sulfate/dermatan sulfate metabolism. Gene Ontology (GO) annotations related to this gene include sulfotransferase activity and isomerase activity. An important paralog of this gene is DSE

OBSERVATIONS

Complication Evidence PMID
Nephropathy1. Here we investigated the association of POL1-nearby variant rs488846, MALT1-nearby variant rs2874116, MC4R-nearby variant rs1942872, PHLPP rs9958800 and DSEL-nearby variant rs9966483 single nucleotide polymorphisms (SNPs) in the 18q region, previously linked with diabetic nephropathy (DN) in African-Americans, with T2DM in (North African) Tunisian subjects, followed by their association with DN, which was performed subsequent to the analysis of the association with T2DM.23727064