ERRFI1
LOCUS ID54206
GENE_SYMBOLERRFI1
GENE NAMEERBB receptor feedback inhibitor 1
SYNONYMNSMIG6, RALT, MIG-6, GENE-33
CHROMOSOME1
HOMOLOGENE ID10344
microRNAsNANA
GENE SUMMARY
ERRFI1 is a cytoplasmic protein whose expression is upregulated with cell growth (Wick et al., 1995 [PubMed 7641805]). It shares significant homology with the protein product of rat gene-33, which is induced during cell stress and mediates cell signaling (Makkinje et al., 2000 [PubMed 10749885]; Fiorentino et al., 2000 [PubMed 11003669]).[supplied by OMIM, Mar 2008]

OBSERVATIONS

Complication Evidence PMID
Nephropathy1. We identify new loci associated with glycemic traits in diabetes and this finding indicates the potential of ERRFI1 as a novel therapeutic target of diabetic nephropathy. "22228707