| ERRFI1 |
| LOCUS ID | 54206 | ||||||||||
| GENE_SYMBOL | ERRFI1 | ||||||||||
| GENE NAME | ERBB receptor feedba | ||||||||||
| SYNONYMNS | MIG6, RALT, MIG-6, GENE-33 | ||||||||||
| CHROMOSOME | 1 | ||||||||||
| HOMOLOGENE ID | 10344 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| ERRFI1 is a cytoplasmic protein whose expression is upregulated with cell growth (Wick et al., 1995 [PubMed 7641805]). It shares significant homology with the protein product of rat gene-33, which is induced during cell stress and mediates cell signaling (Makkinje et al., 2000 [PubMed 10749885]; Fiorentino et al., 2000 [PubMed 11003669]).[supplied by OMIM, Mar 2008] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Nephropathy | 1. We identify new loci associated with glycemic traits in diabetes and this finding indicates the potential of ERRFI1 as a novel therapeutic target of diabetic nephropathy. " | 22228707 |