| FZD5 |
| LOCUS ID | 7855 | ||||||||||
| GENE_SYMBOL | FZD5 | ||||||||||
| GENE NAME | frizzled class recep | ||||||||||
| SYNONYMNS | HFZ5 C2orf31 | ||||||||||
| CHROMOSOME | 2 | ||||||||||
| HOMOLOGENE ID | 2590 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand. [provided by RefSeq, Jul 2008] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Cardiovascular | 1. CONCLUSION: MicroRNA-216b was overexposed in diabetic MMECs and its downregulation may actively enhance angiogenesis in diabetic angiopathy through inverse regulation on FZD5. | 29477872 |