| HNRNPD |
| LOCUS ID | 3184 | ||||||||||
| GENE_SYMBOL | HNRNPD | ||||||||||
| GENE NAME | eterogeneous nuclear | ||||||||||
| SYNONYMNS | P37, AUF1, AUF1A, HNRPD, hnRNPD0 | ||||||||||
| CHROMOSOME | 4 | ||||||||||
| HOMOLOGENE ID | 22410 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Retinopathy | 1. Heterogeneous nuclear ribonucleoprotein D (HNRNPD; degree=33), protein kinase AMP?activated catalytic subunit ?1 (PRKAA1; degree=11), integrin subunit ?4 (ITGA4; degree=8) and ESR1 (degree=8) were identified in the PPI network as high?degree genes. ARHGAP25 (degree=12), HNRNPD (degree=10), HLA?DRB4 (degree=10) and IL23A (degree=9) were high?degree genes identified in the TF?target network. | 30942443 |