IGFBP5
LOCUS ID3488
GENE_SYMBOLIGFBP5
GENE NAMEinsulin like growth
SYNONYMNSIBP5
CHROMOSOME2
HOMOLOGENE ID56489
microRNAsNANA
GENE SUMMARY
IGFBP5 (Insulin Like Growth Factor Binding Protein 5) is a Protein Coding gene. Diseases associated with IGFBP5 include Insulin-Like Growth Factor I and Renal Osteodystrophy. Among its related pathways are Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include fibronectin binding and insulin-like growth factor I binding. An important paralog of this gene is IGFBP3.

OBSERVATIONS

Complication Evidence PMID
Neuropathy1. Dysregulated IGFBP5 expression causes axon degeneration and motoneuron loss in diabetic neuropathy.26025657