IL17F
LOCUS ID112744
GENE_SYMBOLIL17F
GENE NAMEinterleukin 17F
SYNONYMNSML1, ML-1, CANDF6, IL-17F
CHROMOSOME6
HOMOLOGENE ID17115
microRNAsNANA
GENE SUMMARY
The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq, Jul 2008]

OBSERVATIONS

Complication Evidence PMID
Tuberculosis1. In persons with DM or pre-DM, latent infection is characterized by diminished circulating levels of type 1 (interferon ?, interleukin 2, and tumor necrosis factor ?) and type 17 (interleukin 17F) cytokines.24907382