KDM1A
LOCUS ID23028
GENE_SYMBOLKDM1A
GENE NAMElysine demethylase 1A
SYNONYMNSAOF2, CPRF, KDM1, LSD1, BHC110
CHROMOSOME1
HOMOLOGENE ID32240
microRNAsNANA
GENE SUMMARY
This gene encodes a nuclear protein containing a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

OBSERVATIONS

Complication Evidence PMID
Retinopathy1. Thus, the regulation of LSD1 by molecular or pharmacological means has the potential to retard the development of diabetic retinopathy.23423566