LECT2
LOCUS ID3950
GENE_SYMBOLLECT2
GENE NAMEleukocyte cell derived chemotaxin 2
SYNONYMNSchm2, chm-II
CHROMOSOME5
HOMOLOGENE ID1730
microRNAsNANA
GENE SUMMARY
This gene encodes a secreted, 16 kDa protein that acts as a chemotactic factor to neutrophils and stimulates the growth of chondrocytes and osteoblasts. This protein has high sequence similarity to the chondromodulin repeat regions of the chicken myb-induced myeloid 1 protein. A polymorphism in this gene may be associated with rheumatoid arthritis. [provided by RefSeq, Jul 2008]

OBSERVATIONS

Complication Evidence PMID
Retinopathy1. These findings indicated that serum LECT2 level is negatively associated with the presence of DR and suggest that low circulating LECT2 level is a risk factor for DR.27816666