| MTHFD1L |
| LOCUS ID | 25902 | ||||||||||
| GENE_SYMBOL | MTHFD1L | ||||||||||
| GENE NAME | methylenetetrahydrof | ||||||||||
| SYNONYMNS | FTHFSDC1, MTC1THFS, dJ292B18.2 | ||||||||||
| CHROMOSOME | 6 | ||||||||||
| HOMOLOGENE ID | 56706 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| The protein encoded by this gene is involved in the synthesis of tetrahydrofolate (THF) in the mitochondrion. THF is important in the de novo synthesis of purines and thymidylate and in the regeneration of methionine from homocysteine. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2011] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Cardiovascular | 1. We conclude, that rs6922269 variant at MTHFD1L gene could be an important prognostic factor for cardiovascular mortality in patients after ACS. | 25809277 |