NDUFS3
LOCUS ID4722
GENE_SYMBOLNDUFS3
GENE NAMEnuclear factor, erythroid 2
SYNONYMNSp45, NF-E2
CHROMOSOME12
HOMOLOGENE ID4491
microRNAsNANA
GENE SUMMARY
This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial DH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.[provided by RefSeq, Apr 2009]

OBSERVATIONS

Complication Evidence PMID
Nephropathy1. The expressions of NDUFS3 and TGF-BETA1 in DN rats were increased.22903132