| NFE2 |
| LOCUS ID | 4778 | ||||||||||
| GENE_SYMBOL | NFE2 | ||||||||||
| GENE NAME | nuclear factor, eryt | ||||||||||
| SYNONYMNS | p45, NF-E2 | ||||||||||
| CHROMOSOME | 12 | ||||||||||
| HOMOLOGENE ID | 4491 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| NFE2 (Nuclear Factor, Erythroid 2) is a Protein Coding gene. Diseases associated with NFE2 include Polycythemia and Essential Thrombocythemia. Among its related pathways are Factors involved in megakaryocyte development and platelet production and Hematopoietic Stem Cell Differentiation. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and transcription coactivator activity. An important paralog of this gene is NFE2L1. |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Nephropathy | 1. Renal mRNA and protein expressions of NF-E2 related factor 2 (Nrf2) were up-regulated by MG132 in comparison to DN alone. | 21241714 |