| NGB |
| LOCUS ID | 58157 | ||||||||||
| GENE_SYMBOL | NGB | ||||||||||
| GENE NAME | neuroglobin | ||||||||||
| SYNONYMNS | NA | ||||||||||
| CHROMOSOME | 14 | ||||||||||
| HOMOLOGENE ID | 10942 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| This gene encodes an oxygen-binding protein that is distantly related to members of the globin gene family. It is highly conserved among other vertebrates. It is expressed in the central and peripheral nervous system where it may be involved in increasing oxygen availability and providing protection under hypoxic/ischemic conditions. [provided by RefSeq, Jul 2008] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Retinopathy | 1. Approximately 48 and 61 spots were identified in control and diabetic retinopathy respectively, of which three protein spots RBP1 (retinol-binding protein 1), NUD10 (Diphosphoinositol polyphosphohydrolase 3 alpha), NGB (neuroglobin) were down regulated and HBG2 (hemoglobin) and BY55 (CD 160 antigen) were upregulated in diabetic retinopathy. | 26129748 |