NOV
LOCUS ID4856
GENE_SYMBOLNOV
GENE NAMEnephroblastoma overexpressed
SYNONYMNSCCN3, NOVh, IBP-9, IGFBP9, IGFBP-9
CHROMOSOME8
HOMOLOGENE ID1884
microRNAsNANA
GENE SUMMARY
The protein encoded by this gene is a small secreted cysteine-rich protein and a member of the CCN family of regulatory proteins. CNN family proteins associate with the extracellular matrix and play an important role in cardiovascular and skeletal development, fibrosis and cancer development. [provided by RefSeq, Feb 2009]

OBSERVATIONS

Complication Evidence PMID
Nephropathy1. Using the db/db mouse model of diabetic nephropathy, we confirm the expression of CCN3 in the kidney, with temporal localization that supports these in vitro findings.20195391