| NOV |
| LOCUS ID | 4856 | ||||||||||
| GENE_SYMBOL | NOV | ||||||||||
| GENE NAME | nephroblastoma overe | ||||||||||
| SYNONYMNS | CCN3, NOVh, IBP-9, IGFBP9, IGFBP-9 | ||||||||||
| CHROMOSOME | 8 | ||||||||||
| HOMOLOGENE ID | 1884 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| The protein encoded by this gene is a small secreted cysteine-rich protein and a member of the CCN family of regulatory proteins. CNN family proteins associate with the extracellular matrix and play an important role in cardiovascular and skeletal development, fibrosis and cancer development. [provided by RefSeq, Feb 2009] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Nephropathy | 1. Using the db/db mouse model of diabetic nephropathy, we confirm the expression of CCN3 in the kidney, with temporal localization that supports these in vitro findings. | 20195391 |