NOX3
LOCUS ID50508
GENE_SYMBOLNOX3
GENE NAMEDPH oxidase 3
SYNONYMNSMOX-2, GP91-3
CHROMOSOME6
HOMOLOGENE ID49435
microRNAsNANA
GENE SUMMARY
This gene encodes a member of the NOX family of DPH oxidases. These enzymes have the capacity to generate superoxide and other reactive oxygen species (ROS) and transport electrons across the plasma membran

OBSERVATIONS

Complication Evidence PMID
Nephropathy1. Potential candidate genes in these regions that have been implicated in diabetic nephropathy and/or renal damage in models of hypertension include CYBA (or P22PHOX) (16q24), NOX1 (10q22), and NOX3 (6q25.1-q26)17336700