Go to Advanced Search
OXT |
LOCUS ID | 5020 | ||||||||||
GENE_SYMBOL | OXT | ||||||||||
GENE NAME | oxytocin/neurophysin | ||||||||||
SYNONYMNS | OT, OT-NPI, OXT-NPI | ||||||||||
CHROMOSOME | 20 | ||||||||||
HOMOLOGENE ID | 55494 |
microRNAs | NA | NA |
GENE SUMMARY |
---|
This gene encodes a precursor protein that is processed to produce oxytocin and neurophysin I. Oxytocin is a posterior pituitary hormone which is synthesized as an ictive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axolly to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being |
OBSERVATIONS |
---|
Complication | Evidence | PMID |
Cardiovascular | 1. These observations clearly suggest a potential role for OT in replacement therapy for the prevention of cardiovascular complications of diabetes and obesity. | 26102958 |