P2RX2
LOCUS ID22953
GENE_SYMBOLP2RX2
GENE NAMEpurinergic receptor P2X 2
SYNONYMNSP2X2, DF41
CHROMOSOME12
HOMOLOGENE ID14251
microRNAsNANA
GENE SUMMARY
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates syptic transmission between neurons and from neurons to smooth muscle. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Aug 2013]

OBSERVATIONS

Complication Evidence PMID
Neuropathy1. Purinergic receptor signaling transduction pathways might become potential targets for treatment for painful DPN.23090494