PEAR1
LOCUS ID375033
GENE_SYMBOLPEAR1
GENE NAMEplatelet endothelial
SYNONYMNSJEDI, MEGF12
CHROMOSOME1
HOMOLOGENE ID12492
microRNAsNANA
GENE SUMMARY
PEAR1 is a platelet receptor that sigls upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation (nda et al., 2005 [PubMed 15851471]).[supplied by OMIM, Mar 2008]

OBSERVATIONS

Complication Evidence PMID
Cardiovascular1. Our suggest for the first time that genetic variation of PEAR1 is a significant determinant of endothelial function through pathways implicated in cardiovascular disease.26406321