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PEAR1 |
LOCUS ID | 375033 | ||||||||||
GENE_SYMBOL | PEAR1 | ||||||||||
GENE NAME | platelet endothelial | ||||||||||
SYNONYMNS | JEDI, MEGF12 | ||||||||||
CHROMOSOME | 1 | ||||||||||
HOMOLOGENE ID | 12492 |
microRNAs | NA | NA |
GENE SUMMARY |
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PEAR1 is a platelet receptor that sigls upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation (nda et al., 2005 [PubMed 15851471]).[supplied by OMIM, Mar 2008] |
OBSERVATIONS |
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Complication | Evidence | PMID |
Cardiovascular | 1. Our suggest for the first time that genetic variation of PEAR1 is a significant determinant of endothelial function through pathways implicated in cardiovascular disease. | 26406321 |