RBP1
LOCUS ID5947
GENE_SYMBOLRBP1
GENE NAMEretinol binding protein 1
SYNONYMNSCRBP, RBPC, CRBP1, CRBPI, CRABP-I
CHROMOSOME3
HOMOLOGENE ID2175
microRNAsNANA
GENE SUMMARY
This gene encodes the carrier protein involved in the transport of retinol (vitamin A alcohol) from the liver storage site to peripheral tissue. Vitamin A is a fat-soluble vitamin necessary for growth, reproduction, differentiation of epithelial tissues, and vision. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

OBSERVATIONS

Complication Evidence PMID
Retinopathy1. Approximately 48 and 61 spots were identified in control and diabetic retinopathy respectively, of which three protein spots RBP1 (retinol-binding protein 1), NUD10 (Diphosphoinositol polyphosphohydrolase 3 alpha), NGB (neuroglobin) were down regulated and HBG2 (hemoglobin) and BY55 (CD 160 antigen) were upregulated in diabetic retinopathy.26129748