RPS6KA6
LOCUS ID27330
GENE_SYMBOLRPS6KA6
GENE NAMEribosomal protein S6 kinase A6
SYNONYMNSRSK4, PP90RSK4
CHROMOSOMEX
HOMOLOGENE ID22816
microRNAsNANA
GENE SUMMARY
This gene encodes a member of ribosomal S6 kinase family, serine-threonine protein kinases which are regulated by growth factors. The encoded protein may be distinct from other members of this family, however, as studies suggest it is not growth factor dependent and may not participate in the same signaling pathways. [provided by RefSeq, Jan 2010]

OBSERVATIONS

Complication Evidence PMID
Neuropathy1. RSK4 and PAK5 may provide a molecular ratiole for late-stage complications in disease, and further studies are warranted to explore these targets for the treatment of diabetic nephro- and neuropathy, frequently seen in patients with HNF4alpha dysfunction.15615695