| RPS6KA6 |
| LOCUS ID | 27330 | ||||||||||
| GENE_SYMBOL | RPS6KA6 | ||||||||||
| GENE NAME | ribosomal protein S6 | ||||||||||
| SYNONYMNS | RSK4, PP90RSK4 | ||||||||||
| CHROMOSOME | X | ||||||||||
| HOMOLOGENE ID | 22816 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| This gene encodes a member of ribosomal S6 kinase family, serine-threonine protein kinases which are regulated by growth factors. The encoded protein may be distinct from other members of this family, however, as studies suggest it is not growth factor dependent and may not participate in the same signaling pathways. [provided by RefSeq, Jan 2010] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Neuropathy | 1. RSK4 and PAK5 may provide a molecular ratiole for late-stage complications in disease, and further studies are warranted to explore these targets for the treatment of diabetic nephro- and neuropathy, frequently seen in patients with HNF4alpha dysfunction. | 15615695 |