SGK3
LOCUS ID23678
GENE_SYMBOLSGK3
GENE NAMEserum/glucocorticoid regulated kinase family, member 3
SYNONYMNSCISK, SGK2, SGKL
CHROMOSOME8
HOMOLOGENE ID56582
microRNAsNANA
GENE SUMMARY
This gene is a member of the Ser/Thr protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chloride channels. Alterte transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

OBSERVATIONS

Complication Evidence PMID
Nephropathy1. SGK2 and SGK3 mRNA were elevated in DN mice.16116964