SLC30A8
LOCUS ID169026
GENE_SYMBOLSLC30A8
GENE NAMEsolute carrier family 30 (zinc transporter), member 8
SYNONYMNSZNT8, ZnT-8
CHROMOSOME8
HOMOLOGENE ID13795
microRNAsNANA
GENE SUMMARY
The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans.

OBSERVATIONS

Complication Evidence PMID
Nephropathy1. Polymorphisms of SLC30A8 and TCF7L2 genes may be associated with the development of DR and DN, respectively. Association between the polymorphisms of CKDAL1, TCF7L2 and HHEX genes and DR, and between the polymorphisms of SLC30A8, HHEX and CDKAL1 genes and DN, cannot be excluded.22487833