| TM6SF2 |
| LOCUS ID | 53345 | ||||||||||
| GENE_SYMBOL | TM6SF2 | ||||||||||
| GENE NAME | transmembrane 6 supe | ||||||||||
| SYNONYMNS | NA | ||||||||||
| CHROMOSOME | 19 | ||||||||||
| HOMOLOGENE ID | 77694 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| TM6SF2 (Transmembrane 6 Superfamily Member 2) is a Protein Coding gene. Diseases associated with TM6SF2 include Non-Alcoholic Fatty Liver Disease and Nodular Nonsuppurative Panniculitis. An important paralog of this gene is TM6SF1. |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Cardiovascular | 1. Obese/Metabolic NAFLD due to the PNPLA3 or TM6SF2 genetic variants predisposes to type 2 diabetes and cardiovascular disease. | 27128911 |