TRPA1
LOCUS ID8989
GENE_SYMBOLTRPA1
GENE NAMEtransient receptor potential cation channel subfamily A member 1
SYNONYMNSFEPS, ANKTM1
CHROMOSOME8
HOMOLOGENE ID7189
microRNAsNANA
GENE SUMMARY
The structure of the protein encoded by this gene is highly related to both the protein ankyrin and transmembrane proteins. The specific function of this protein has not yet been determined; however, studies indicate the function may involve a role in signal transduction and growth control. [provided by RefSeq, Jul 2008]

OBSERVATIONS

Complication Evidence PMID
Neuropathy1. The indicate that the TRPA1 channel exerts an important role in the pathogenesis of peripheral diabetic neuropathy (PDN). Blocking the TRPA1 channel provides a selective disease-modifying treatment of PDN.22133672