USF2
LOCUS ID7392
GENE_SYMBOLUSF2
GENE NAMEupstream transcription factor 2, c-fos interacting
SYNONYMNSFIP, bHLHb12
CHROMOSOME19
HOMOLOGENE ID2527
microRNAsNANA
GENE SUMMARY
This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

OBSERVATIONS

Complication Evidence PMID
Nephropathy1. These findings suggest that overexpression of USF2 accelerates the development of diabetic nephropathy.17881461