A Gene Atlas of Type 2 Diabetes Mellitus Associated Complex Disorders
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CXCL16 |
LOCUS ID | 58191 | ||||
GENE_SYMBOL | CXCL16 | ||||
GENE NAME | chemokine (C-X-C motif) ligand 16 | ||||
SYNONYMNS | SRPSOX CXCLG16 SR-PSOX | ||||
CHROMOSOME | 17 | ||||
HOMOLOGENE ID | 49694 | ||||
SOURCE | HUMAN |
PMIDs | 24489966 |
GENE SUMMARY |
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OBSERVATION |
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1. Serum CXCL16 may be an indicator of renal injury in subjects with T2DM. Understanding the exact mechanism of elevated CXCL16 in subjects with DN requires further study. this study provides clinical evidence revealing that serum concentrations of CXCL16 are increased in subjects with DN and are independently associated with the loss of renal function. These data imply that CXCL16 may be a novel marker that predicts renal injury in T2DM subjects |