A Gene Atlas of Type 2 Diabetes Mellitus Associated Complex Disorders
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FGF21 |
LOCUS ID | 26291 | ||||
GENE_SYMBOL | FGF21 | ||||
GENE NAME | fibroblast growth factor 21 | ||||
SYNONYMNS | |||||
CHROMOSOME | 19 | ||||
HOMOLOGENE ID | 10428 | ||||
SOURCE | HUMAN |
PMIDs | 25625802 |
GENE SUMMARY |
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The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this growth factor has not yet been determined. [provided by RefSeq, Jul 2008] |
OBSERVATION |
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1. Elevated serum FGF21 levels may be a useful biomarker for predicting kidney disease progression especially in early stages of diabetic nephropathy. |